Generative AI (GenAI) can generate high-resolution and complex content mimicking the creativity of humans, thereby benefiting industries such as SHOPSTORM_HIDDEN_PRODUCT gaming, entertainment, and product design.In recent times, AI-generated fake videos, commonly referred to as deepfakes, have become more commonplace and convincing.An additional de
Systemic primary carnitine deficiency (SPCD) is an autosomal recessive Tudca inborn error of fatty acid metabolism caused by a defect in the transporter responsible for moving carnitine across plasma membrane.The clinical features of SPCD vary widely based on the age of onset and organs involved.During infancy, patients might show episodes of hypok
Immune checkpoint blockade of programmed cell death protein 1 (PD-1) had an impressive long-lasting effect in a portion of advanced-stage melanoma patients, however, this therapy failed to induce responses in several patients; how to increase the objective response rate is very important.Cellular FLICE-inhibitory protein (c-FLIP) could inhibit apop
Current anticholinesterase pesticides were developed during World War II and are toxic to mammals because they target a catalytic serine residue of acetylcholinesterases (AChEs) in insects and in mammals.A sequence analysis of AChEs from 73 species and a three-dimensional model of a malaria-carrying mosquito (Anopheles gambiae) AChE (AgAChE) report